Daily Archives May 8, 2019

Sterile compounding methods – Info

Sterility assurance level (SAL) is a microbiology process that describes the probability of a single unit of being non-sterile after subjected to sterilization. Microbiologists stated that it’s impossible to prove that all organisms are eliminated. The reasons behind are as follows: organisms could be present yet undetectable and/or not incubated in their preferred environment. Probably, their existence has not been discovered yet. Hence this system is used. SAL is like an intelligent guess that all organisms are killed off after being sterilized. No wonder that medical device manufacturers used this procedure for their products.

Manufacturers designed their sterilization processes with very low SAL. This means that one in a million of their devices are considered non-sterile. A very high SAL means high probability of the sterilization process efficiency in killing organisms. The recommended survival probability for organisms set on a sterilized device is a SAL of 10-6. This level is also used on the whole microbial population contained in a device. A 10-1 log reduction means that 90% of the microbial group is reduced. The more this reduction rate is used, the higher reduction rate. So the experts try to achieve a 6 log (10-6) reduction to deduct a million of microbes close to zero.Read more about sterile compounding methods .

Control is achieved in the aseptic process by using sterile components; both inside and outside of the said process. IV bags, vials and ampoules have undergone aseptic processing. Medical manufacturers used them in their compounded sterilized products. Take note that prior to the development of Advanced Aseptic Compounding of the CTG, the exterior of these devices were not sterilized. At that time, there are no known ways to effectively decontaminate the external surfaces of those devices. This process cannot be repeated also.

Consistent decontamination process was provided by the MIC-EDU through its Advanced Aseptic Compounding technology. The process is repeatable to decontaminate both the exterior and interior surfaces of a device. A 10-6 reduction rate is also used in this system. Each reduction load utilized chemical indicators to check that decontamination is effectively done. The US FDA has a Medical Device Reporting Program or MedWatch, to determine if there is an increased infection of a medical product. MedWatch checks whether those devices labeled with “sterile” but don’t have a SAL of 10-6 level. Medical devices checked include sterilization-sensitive types, combination types, and cell or tissue-based types.

Sterility Assurance Level (SAL) has helped in determining safe medical products through the years. But it’s not perfect. Still many medical companies used it as a reliable system for device decontamination. To date, no established relationship between specific SAL rates and product safety intended for use in the actual environment. However, indicators like the SAL of 10-3 to 10-6 may provide a likelihood of adequate assurance against medical device infections. Medical manufacturers continue to adhere to these standards, until a new and more effective one comes along. When it does, improvements are expected. Still, additional researches are being done; in a hope that the detection rate of infections will be greatly improved in the near future.

A Guide To Plumbing Manassas

The term ‘contractor’ is used for a person indulged in the construction services. And construction includes building new structures, roads or dams as well as modifying or repairing the existing ones. Further the role is divided into different types of contractor depending on nature of construction work handled by them. For instance, if you are planning to build a new home, you would need services of building contractors, electrical contractors, remodeling contractors, painting contractors, plumbing contracts, landscapers etc. Plumbing contractor is a person who is involved with plumbing works like laying pipelines and fixing plumbing fittings like bath tubs, sinks, faucets, toilets etc.

You would need the services of a plumbing contractor at the time of building your new house as well as for maintenance of your old plumbing fittings. When you are constructing a new home, the amount of plumb work required is too comprehensive. You should discuss the plumbing requirements with your main contractor. He must have appointed a plumber for all the immediate plumbing needs like laying main pipes and fitting bathroom fixtures etc. however, if you wish to appoint a different plumbing contractor, then you can ask your building contractor to cooperate with your decisions. A plumbing contractor should work in close coordination with the building contractor. A plumber should have a clear idea about the building’s layout and foundation in order to create a proper foundation for underground plumbing fittings.Check out this site Plumbing Manassas.

If your plumbing works are too extensive it would be wise to appoint a reputed plumbing contractor to oversea the entire plumbing division of your construction. However, finding a reliable contractor who can deliver you with quality plumbing fixtures and equipments is a challenging job. There are many factors to be considered before finalizing the contract with a plumbing service or company. You should not sign up the deal with the first plumbing service you come across. You should only hire the services of a reputed plumbing company or contractor who has years of experience to boast about.

You can search for feasible plumbing contractor in your locality by initiating a casual online search. There are online directories where you will find hundreds of plumbing services listed along with their contact numbers and address. You can enquire the nature of service and rates quoted by each of these contractors by placing a direct call.

If you have any specific demands you should discuss the same with a potential plumbing contractor before finalizing the agreement or paying the advance sum. Ideally, a plumber should accommodate his services as per your demands rather than thrusting his opinions on you. Further, he should be able to procure all the hardware requirements at cheaper rates. These contractors have connection with many hardware dealers, so it wouldn’t be tough for them to procure bulk orders at economic rates.

Finally, you should enquire about the past working history of your contractor. You can visit a few house owners with whom your contractor has worked with. This would give you a fair idea about the nature and quality of his service.